Chronic insomnia and methods of its correction (the results of the clinical study)

Authors

  • T.S. Mishchenko V.N. Karazin Kharkiv National University, Kharkiv, Ukraine
  • L.P. Zabrodina SI “Institute of Neurology, Psychiatry and Narcology” of the National Academy of Medical Sciences of Ukraine, Kharkiv, Ukraine
  • V.N. Mishchenko SI “Institute of Neurology, Psychiatry and Narcology” of the National Academy of Medical Sciences of Ukraine, Kharkiv, Ukraine
  • Yu.V. Bovt SI “Institute of Neurology, Psychiatry and Narcology” of the National Academy of Medical Sciences of Ukraine, Kharkiv, Ukraine

DOI:

https://doi.org/10.22141/2224-0713.17.8.2021.250817

Keywords:

insomnia, subjective sleep scores questionnaire, ­Epworth questionnaire, polysomnography, Levana® IC

Abstract

The article considers the classification, risk factors, pathophysiology, pathogenesis, and methods of treatment of insomnia — the most common type of sleep disorders. The authors present the results of a study aimed at analyzing the efficacy and safety of Levana® IC compared to Imovan® in the treatment of insomnia. Sixty patients with clinical symptoms of primary chronic insomnia were involved. The treatment lasted for 14 days. To assess the effectiveness of treatment, the following research methods were used: psychodiagnostic (using questionnaires), polysomnography, statistical. The study showed that Levana® IC demonstrated rapid development of clinical efficacy by most qualitative and quantitative indicators of sleep assessment, which was confirmed by polysomnography results.

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References

Ellis J.G., Perils M.L., Bastien C.H., Gardani M., Espie C.A. The Natural History of Insomnia: Acute Insomnia and First-onset Depression. Sleep. 2014. 37(1). 97-106. https://doi.org/10.5665/sleep.3316.

Roth T. Insomnia: definition, prevalence, etiology, and consequences. J. Clin. Sleep Med. 2007. 3 (Suppl. 5). 7-10.

Мищенко В.Н., Бовт Ю.В., Забродина Л.П., Мищенко В.К. Особенности нарушения структуры ночного сна у пациентов с болезнью мелких сосудов. Український вісник психоневрології. 2018. Т. 26. Вип. 4(97). С. 32-38.

Eguchi K., Hoshide S., Ishikawa S. et al. Short sleep duration is an blindent predictor of stroke events in elderly hypertensive patients. J. Hypertens. 2010. 4(5). 255-262. https://doi.org/10.10l6/jjash.2010.09.001.

Gianfagna F., Veronesi G., Bertu L. et al. Influence of sleep disturbances on age at onset and long-term incidence of major cardiovascular events: the monica-brianza and pamela cohort studies. Sleep Med. 2016. 21. 126-132. https://dx.doi.Org/10.10l6/j.sleep.2016.01.007.

Мищенко В.Н., Забродина Л.П., Мищенко Т.С. Нарушения сна и его коррекция у больных с дисциркуляторной энцефалопатией. Психіатрія, неврологія та медична психологія. 2019. Вип. 11. С. 38-50. DOI: 10.26565/2312-5675-2019-12-05.

Riemann D., Baglioni C., Bassetti C., Bjorvatn B. et al. European guideline for the diagnosis and treatment of insomnia. Journal of Sleep Research. 2017. 26(6). 675-700. https://doi.org/10.1111/jsr.12594.

American Academy of Sleep Medicine. International classification of sleep disorders, 3nd ed.: Diagnostic and coding manual. Westchester, Ill.: American Academy of Sleep Medicine, 2014.

Ellis J.G., Gehrman P., Espic C.A., Riemann D., Pcrlis M.L. Acute insomnia: Current conceptualizations and future directions. Sleep Medicine Reviews. 2012. 16(1). 5-14. https://doi.Org/10.1016/j.smrv.2011.02.002.

Ohayon M.M. Epidemiology of insomnia: what we know and what we still need to learn. Sleep Med. Rev. 2002. 6(2). 97-111. https://doi.org/10.1053/smrv.2002.0186.

Michael M.L. Etiology and Pathophysiology of Insomnia. Principles and practice of sleep medicine / Kryger M., Roth T., De-ment W.C., eds. Elsevier, Inc.: Philadelphia, 2016. 769-784.

Мельников А.Ю. Острая инсомния: естественное течение и возможности коррекции. Журн. неврологии и психиатрии им. С.С. Корсакова. Спецвып. 2019. 119. 28-35.

Wilson S.J., Nutt D.J., Alford et al. British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders. J. Psychopharmacol. 2010. 24. 1577-601.

Левин Я.И. Мелатонин в неврологической практике. Consilium Medicum. 2012. 2. 111-115.

Shepertycky M.R., Banno K., Kryger MH. Differences between men and women in the clinical presentation of patients diagnosed with obstructive sleep apnea syndrome. Sleep. 2005. 28. 309-14.

Franklin K.A., Anttila H., Axelsson S. et al. Effects and side-effects of surgery for snoring and obstructive sleep apnea — a systematic review. Sleep. 2009. 32. 27-36.

Бурчаков Д.И., Тардов М.В. Инсомния (бессонница): причины, методы лечения и клинические ситуации. Consilium Medicum. 2020. № 22(2). С. 75-82. https://doi.org/10.26442/20751753.2020.2.200101.

Ковальзон В.М. Роль гистаминергической системы головного мозга в регуляции цикла бодрствование-сон. Физиология человека. 2013. 39. 13-23.

Дубенко А.Е., Бабкина Ю.А. Инсомнии: критерии постановки диагноза и клинические особенности у взрослых пациентов. Нейроnews. 2019. № 1(102). С. 31-38.

Vinkers C.H., Olivier B. Mechanisms Underlying Tolerance after Long-Term Benzodiazepine Use: A Future for Subtype-Selective GABA(A) Receptor Modulators. Adv. Pharmacol. Sci. 2012. 2012. 416864.

Sleep computing committee of the japanese society of sleep research society (JSSR): et al. Proposed supplements and amendments to ‘a manual of standardized terminology, techniques and scoring system for sleep stages of human subjects’, the Rechtschaffen & Kales (1968) standard. Psychiatry and clinical neurosciences. 2001. Vol. 55. № 3. С. 305-310.

Вейн А.М., Левин Я.И. Принципы современной фармакотерапии инсомний. Журнал неврологии и психиатрии. 1998. № 5. С. 39-43.

Published

2022-01-31

How to Cite

Mishchenko, T., Zabrodina, L., Mishchenko, V., & Bovt, Y. (2022). Chronic insomnia and methods of its correction (the results of the clinical study). INTERNATIONAL NEUROLOGICAL JOURNAL, 17(8), 16–25. https://doi.org/10.22141/2224-0713.17.8.2021.250817

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Original Researches

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