Citicoline Application in Patients with Hypertensive Dyscirculatory Encephalopathy and Concomitant Hypothyroidism

Authors

  • O.Ye. Kovalenko State Scientific Institution «Scientific-Practical Centre of Preventive and Clinical Medicine» of State Affairs Department, Kyiv National Medical Academy of Postgraduate Education named after P.L. Shupyk, Kyiv, Ukraine
  • O.V. Lytvyn State Scientific Institution «Scientific-Practical Centre of Preventive and Clinical Medicine» of State Affairs Department, Kyiv

DOI:

https://doi.org/10.22141/2224-0713.3.57.2013.85427

Keywords:

hypertensive dyscirculatory encephalopathy, hypothyroidism, cognitive impairment, MMSE scales, memory, perception, speech, orientation, anxiety and depressive disorders, Spielberger — Khanin anxiety scale, citicoline

Abstract

Clinical course of hypertensive dyscirculatory encephalopathy (HDE), complicated with hypothyroidism, requires optimization of pathogenetic treatment that should meet the current requirements of medicine and pharmacology. A clinical neurological study has been carried out to determine cognitive state and state of anxiety and depressive disorders in 60 patients after basic treatment with therapy with citicoline. Results were compared with parameters of 30 patients after carrying out basic treatment. The study demonstrates, that use of citicoline in treating patients with HDE and concomitant hypothyroidism leads to regression of vestibulo-ataxic disorders, improvement of mnestical function, reduction of anxiety disorders compared with patients who received only basic therapy. Thus, due to neurotransmitter, neurometabolic, antiplatelet effect citicoline deserves the prospects for further implementation in the treatment of pathology complicated with hypothyroidism.

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Published

2013-01-10

How to Cite

Kovalenko, O., & Lytvyn, O. (2013). Citicoline Application in Patients with Hypertensive Dyscirculatory Encephalopathy and Concomitant Hypothyroidism. INTERNATIONAL NEUROLOGICAL JOURNAL, (3.57), 111–115. https://doi.org/10.22141/2224-0713.3.57.2013.85427

Issue

Section

To practicing Neurologist

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