DOI: https://doi.org/10.22141/2224-0713.1.87.2017.96538

Non-motor symptoms in clinical picture of the Parkinson’s disease

I.N. Karaban, O.V. Shalenko, S.A. Kryzhanovskiy

Abstract


Our study included 122 patients suffering from the Parkinson disease (PD), Hoehn and Yahr stage 2.0–3.0 aged 45–59 years (n = 62) and 60–74 years (n = 60). We used the following assessment instruments to evaluate the severity of various non-motor symptoms (NMS): the Non-Motor Symptoms Scale-Parkinson’s Disease (NMSS-PD), Beck Depression Inventory, the Epworth Sleepiness Scale, Wein Questionnaire of autonomic disturbances, Mini-Mental State Examination, Montreal Cognitive Assessment, Frontal Assessment Battery and the State-Trait Anxiety Inventory. The informativeness of NMSS was found as an instrument for age characteristics of NMS at PD. Our findings indicate the high NMS incidence in the PD patients of various age groups, the dependence of the degree of severity on the disease duration, and the high risk for developing emotional disorders or depression.

Keywords


Parkinson’s disease; non-motor symptoms; Non-Motor Symptoms Scale-Parkinson’s Disease

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