DOI: https://doi.org/10.22141/2224-0713.8.62.2013.86122

Peculiarities of Cerebral Hemodynamics and Vascular Autoregulation in Chronic Brain Ischemia

Kozyolkin A.A. Kozyolkin A.A., S.V. Yarkova

Abstract


Eighty patients were examined. Sixty one of them had dyscirculatory encephalopathy II stage. They were divided into two groups differed by treatment mode. Namely, the patients of the first group got L-arginine and the patients from the control did not use it. The cerebral hemodynamics in the patients was examined through the duplex scanning of extra- and intracranial arteries. According to the results there were found significantly improved hemodynamic parameters in the patients with dyscirculatory encephalopathy II stage treated with L-arginine.


Keywords


cerebrovascular diseases; endothelial dysfunction; cerebral hemodynamics; cerebrovascular reactivity; L-arginine

References


Бабушкина А.В. L-аргинин с точки зрения доказательной медицины / А.В. Бабушкина // Укр. мед. часопис. — 2009. — № 6(74). — С. 43-48.

Волошин П.В. Эндотелиальная дисфункция при цереброваскулярной патологии / П.В. Волошин, В.А. Малахов, В.А. Завгородняя. — Харьков, 2006. — 92 с.

Гусев Е.И. Ишемия головного мозга / Е.И. Гусев, В.И. Скворцова. — М.: Медицина, 2001. — 328 с.

Лелюк В.Г. Ультразвуковая ангиология / В.Г. Лелюк, С.Э. Лелюк. — М.: Реальное Время, 2003. — 322 с.

Малая Л.Т. Эндотелиальная дисфункция при патологии сердечно-сосудистой системы / Л.Т. Малая, А.Н. Корж, Л.Б. Балковая. — Харьков: Форсинг, 2000. — 432 с.

Мищенко Т.С. Достижения в области сосудистых заболеваний головного мозга за последние 2 года / Т.С. Мищенко // Здоров’я України. — 2010. — № 5. — С. 12-13.

Alves Pereira I., Ferreira Borba E. The role of inflammation, humoral and cell mediated autoimmunity in the pathogenesis of atherosclerosis // Swiss. Med. Wkly. — 2008. — Vol. 138(37–38). — P. 534-539.

Bai Y., Sun L., Yang T. et al. Increase in fasting vascular endothelial function after short-term oral L-arginine is effective when baseline flow-mediated dilation is low: a meta-analysis of randomized controlled trials // Am. J. Clin. Nutr. — 2009. — Vol. 89(1). — Р. 77-84.

Böger R.H. The pharmacodynamics of L-arginine // J. Nutr. — 2007. — Vol. 137. — Р. 1650-1655.

Michael T., Gewaltig M., Kojda G. Vasoprotection by nitric oxide: mechanisms and therapeutic potential // Cardiovascular research. — 2002. — Vol. 55. — P. 205-260.

Vanhoutte P.M. Endothelial dysfunction: the first step toward coronary arteriosclerosis // Circ. J. — 2009. — Vol. 73(4). — P. 595-601.




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