Clinical and MRI Comparisons for Manifestations of Brain Damage in Multiple Sclerosis in Their Pathogenic Presentation

O.O. Yarosh, O.V. Sayko

Abstract


63 patients with different clinical forms of multiple sclerosis and stages of its clinical course had been examined. The basis for the diagnosis of the disease were the following criteria, including their combination: complaints and medical history for this disease; substantive clinical symptoms, which manifested with multiple lesions of phylogenetically young conducting pathways; intermittent or intermittent-progressive clinical course of the disease with signs of instability; appearance of illness mainly in young age, and also the presence of immunopathological disorders. This work proved that magnetic resonance imaging examination is not able to determine the pathomorphological nature of affected brain substance, including varieties of periaxial process, one of which is demyelinisating one which associates multiple sclerosis. Therefore, analysis of clinical picture of the pathology of specified disease underlies its recognition, taking into account the results of paraclinical methods of investigation.

Keywords


multiple sclerosis; magnetic resonance imaging; clinical assessment of neurological status

References


Бисага Г.Н. Современные методы инструментальной диагностики и иммунокорригирующей терапии рассеянного склероза: Автореф. дис... канд. мед. наук — СПб., 1993.

Головкин В.И., Бисага Г.Н. Магнитно-резонансные изменения при различных клинических проявлениях рассеянного склероза // Клин. применение магнитно-резонансной томографии: Тез. докл. науч. конф. — Л.: ВМедА, 1991. — С. 27-28.

Головкин В.И., Бисага Г.Н. Клинико-магнитно-резонансно-томографические соотношения при рассеянном склерозе // Неврологический журнал. — 1997. — Вып. 3. — С. 26-29.

Патология серого вещества при рассеянном склерозе // The Lancet Neurology (Ukrainian Edition). — 2012. — № 1 (34). — С. 6.

Ярош А.А. Этиология, патогенез, клиника и лечение рассеянного склероза: Автореф. дис... д-ра мед. наук. — К., 1992.

Arnold D.L. Magnetic resonance spectroscopy: imaging axonal damage in MS // J. Neuroimmunol. — 1999. — Vol. 98 (1). — Р. 2-6.

Paty D.W., Kooopmans R.A., Redekop W.K., Oger J.J.F., Kastrukoff L.F., Li D.K.B. Does the MRI activity rate predict the clinical course of MS? // Neurology. — 1992. — 42, Suppl. 3. — 427.

Pozdnjakov A.V., Bisaga G.N., Tjutin L.A., Golovkin V.I. Proton magnetic resonance spectroscopy in different types of multiple sclerosis // Multiple sclerosis. — 1998. — Vol. 4, № 4. — Р. 296.

Sreeram V. Ramagopalan, Ruth Dobson, Ute C. Meier, Gavin Giovannoni. Рассеянный склероз: факторы риска, продромальная фаза и вероятные причинные связи // The Lancet Neurology (Ukrainian Edition). — 2012. — № 2 (35). — С. 36-51.




DOI: https://doi.org/10.22141/2224-0713.1.55.2013.85620

Refbacks

  • There are currently no refbacks.


Copyright (c) 2016 INTERNATIONAL NEUROLOGICAL JOURNAL

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

 

© Publishing House Zaslavsky, 1997-2017

 

 Яндекс.МетрикаSeo анализ сайта Рейтинг@Mail.ru