Features of Electroencephalogram Changes in Children with Drug-Resistant Forms of Epilepsy

A.V. Voronova


Comparative analysis of EEG in 64 children with drug-resistant epilepsy and in 26 children with remediable forms of epilepsy was performed. A visual assessment of EEG patterns, as well as quantitative assessment of non-specific changes in brain activity, the average interval between epileptic discharges, the number of epileptic foci were conducted depending on drug-resistant or epileptic encephalopathy being diagnosed.
It was shown that according to the only visual analysis of the EEG was shown to be not remarkable for differentiating drug-resistant and remediable forms of epilepsy. The exceptions were specific nosological patterns: burst suppression ones, hypsarrhythmia, generalized complexes sharp — slow wave. There was found a correlation between drug-resistance and epileptic encephalopathy development with non-specific changes in intensity and the epileptic foci number. Development of epileptic encephalopathy iis associated with increased frequency of paroxysmal discharges in EEG.


vdrug-resistant forms of epilepsy in children; EEG patterns


Бунчук М.М., Номеровская А.А., Воронова А.В. Динамика заболеваемости эпилепсией и эпилептическими синдромами у младенцев и детей в АРК за 5 лет (2007–2011 гг.) // Международный неврологический журнал. — 2012. — № 6 (52). — С. 27-30.

Евтушенко С.К., Омельяненко А.А. Клиническая электроэнцефалография у детей. — Донецк, 2005. — 880 с.

Евтушенко С.К., Омельяненко А.А., Шестова Е.П., Морозова Т.М. Прогрессирующие формы эпилептических энцефалопатий у младенцев и детей (трудности диагностики и терапии) // Український вісник психоневрологiї. — 2013. — Т. 21, № 3 (76). — С. 123-127.

Мухин К.Ю., Петрухин А.С., Холин А.А. Эпилептические энцефалопатии и схожие синдромы у детей. — М.: АртСервис Лтд, 2011. — 680 с.

Filippini M., Boni A., Giannotta M., Gobbi G. Neuropsychological development in children belonging to BECTS spectrum: long-term effect of epileptiform activity // Epilepsy Behav. — 2013. — V. 28 (3). — P. 504-511.

Holmes G. EEG abnormalities as a biomarker for cognitive comorbidities in pharmacoresistant epilepsy // Epilepsia. — 2013. — V. 54 (Suppl. 2). — P. 60-62.

Lado F., Rubboli G., Capovilla P., Avanzini G., Moshй S. Pathophysiology of epileptic encephalopathies // Epilepsia. — 2013. — V. 54 (Suppl. 8). — P. 6-13.

Noachtar S., Remi J. The role of EEG in epilepsy: A critical review // Epilepsy & Behavior. — 2009. — V. 15. — P. 22-33.

Pitkдnen A., Lukasiuk K. Mechanisms of epileptogenesis and potential treatment targets // Lancet Neurol. — 2011. — V. 10. — P. 173-186.

Steinhoff B., Scholly J., Dentel C., Staack A. Is routine electroencephalography (EEG) a useful biomarker for pharmacoresistant epilepsy? // Epilepsia. — 2013. — V. 54 (Suppl. 2). — P. 63-66


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