Application of Choline Alfoscerate in Patients with Acute Ischemic Stroke

V.A. Yavorska, Yu.V. Pershina, O.B. Bondar, A.V. Filippov, Ye.N. Belevtsova


The efficiency of choline alfoscerate in patients in the acute phase of ischemic stroke has been studied. Its use has a significant effect on the recovery of motor and speech functions. There has been noted earlier recovery of consciousness and a beneficial effect on mental activity, productive thinking, memory, and social adaptation of patients as a whole.


stroke; choline alfoscerate; efficiency; recovery


Верещагин Е.В., Ганнушкина И.В., Суслика З.А. и др. Очерки ангионеврологии. — М., 2005.

Яворская В.А. Сосудистые заболевания головного мозга: Рук-во для семейных врачей. — Х., 2003. — 238 с.

Adams H.P., Zoppo G., Alberts M.J. et al. Guidelines for the early management of adults with ischemic stroke // Circulation. — 2007. — Vol. 115. — P. 478-534.

Aguglia E., Ban T.A., Panzarasa R.M. et al. Choline alphoscerate in the treatment of mental pathology following acute cerebrovascular accident // Func. Neurol. — 1993. — Vol. 8. — P. S5-S24.

Barbagallo Sangiorgi G., Barbagallo M., Giordano M. et al. Alphalycerophosphocholine in the mental recovery of cerebral ischemic attacks. An Italian multicenter clinical trial // Ann. N. Y. Acad. Sci. — 1994. — Vol. 717. — P. 253-269.

Consoli D., Giunta V., Grillo G. et al. AlphaGPC 89 in the treatment of acute cerebrovascular accident patients // Arch. Med. Interna. — 1993. — Vol. 45. — P. 13-23.

Davalos A., Castillo J., Alvarez-Sabin J. et al. Oral citicoline in acuteischemic stroke. Аn individual patient data pooling analysis of clinical trials // Stroke. — 2002. — Vol. 33. — P. 2850-2857.

Gambi D., Onofrj M. Multicenter clinical study of efficacy and tolerability of choline alfoscerate in patients with deficits in higher mental function arising after an acute ischemic cerebrovascular attack // Geriatria. — 1994. — № 6. — P. 91-98.

Goldstein L.B. Acute ischemic stroke treatment in 2007 //Circulation. — 2007. — Vol. 116. — P. 1504-1514.

Rogalewski А., Shneider A., Ringelstain E.B., Shnabitz W.F. Toward amultimodal neuroprotective treatment of stroke // Stroke. — 2006. — Vol. 37. — P. 1129-1136.

Tomasina C., Manzino M., Novello P. et al. Clinical study of the therapeutic effectiveness and tolerability of choline alfoscerate in 15 subjects with compromised cognitive functions subsequent to acute focal cerebral ischemia // Riv. Neuropsichiatr. Sci. Affin. — 1996. — Vol. 37. — P. 21-28.


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.


© Publishing House Zaslavsky, 1997-2020


   Seo анализ сайта