Perinatal Risk Factors for Hypoxic-Ischemic Encephalopathy in Full-Term Infants with Normal and Low to the Gestational Age Body Weight
Keywords:hypoxic-ischemic encephalopathy, low to the gestational age body weight, perinatal risk factors
In the department of neonatal pathology of the Chernivtsi regional children’s clinical hospital, 41 full-term newborns with hypoxic-ischemic encephalopathy have been examined with the aim of studying perinatal risk factors of the disease depending on birth weight. It is found that the main predictors of hypoxic-ischemic encephalopathy in small for gestational age infants were: mothers’ residence in urban areas (46.2 %); presence of chronic maternal disease (anemia, thyroid pathology) during pregnancy (46.6 %); concomitant congenital malformations in one third (30.8 %) of newborns; development of respiratory disorders at birth, requiring artificial lung ventilation (61.5 %); infants’ feeding problems (61.5 %). Hypoxic-ischemic lesions of the central nervous system in full-term neonates with adequate to the gestational age body weight were preceded by: pathological course of intrapartum period (fetal distress during labor due to tight nuchal cord in one fourth of cases and pathological delivery in one third (32.1 %) of cases), associated with the birth of one-third of neonates with asphyxia (Apgar 1st minute test ≤ 4 points), which often led to the development of cardiogenic complications (28.6 %), multiple organ failure (14.3 %) and seizure syndrome (17.9 %).
Pal'chyk A.B. Hypoksychesky-yshemycheskaya entsefalopatyya novorozhdennih / A.B. Pal'chyk, N.P. Shabalov. – 4-e yzd., yspr. y dop. – M.: MED-press-ynform, 2013. – 288 s.
Posledstvyya perynatal'nikh porazhenyy tsentral'noy nervnoy systemi: dyskussyonnie voprosi / A.P. Volosovets, S.P. Kryvopustov, Y.A. Lohynova, M.A. Shakot'ko // Zdorov'e rebenka. – 2008. - #4 (13). – S. 101-106.
Antepartum and Intrapartum Factors Preceding Neonatal Hypoxic-Ischemic Encephalopathy M. Martinez-Biarge, J. Diez-Sebastian, C.J. Wusthoff, E. Mercuri, F.M. Cowan Pediatrics 2013;132;e952; originally published online September 9, 2013; DOI: 10.1542/peds.2013-0511
Risk factors for hypoxic-ischaemic encephalopathy in asphyxiated newborn infants / S. Futrakul, P. Praisuwanna, P. Thaitumyanon J Med Assoc Thai 2006; 89 (3): 322-8; http://www.medassocthai.org/journal
Incidence and prediction of outcome in hypoxic-ischaemic encephalopathy in Japan M. Hayakawa, Y. Ito, S. Saito, N. Mitsuda [et al] Pediatrics International 2014;56:215–221; doi: 10.1111/ped.12233
Obstetric aspects of hypoxic ischemic encephalopathy S. Kumar, S. Paterson-Brown Early Hum Dev. 2010 Jun;86(6):339-44. doi: 10.1016/j.earlhumdev.2010.05.009.
Perinatal morbidity and risk of hypoxic-ischaemic encephalopathy assotiated with intrapartum sentinel events M. Martinez-Biarge, R. Madero, A. Gonzalez, J. Quero [et al] Am J Obstet Gynecol 2012;206:148-154; doi: 10.1016/j.ajog.2011.09.031
Prediction of perinatal hypoxic encephalopathy: proximal risk factors and short-term complications T.Y.Y. Zamzami, S.A. Al-Saedi, A.M. Marzouki, H.A. Nasrat J Clin Gynecol Obstet. 2014;3(3):97-104; doi: http://dx.doi.org/10.14740/jcgo267w
Risk factors for low birth weight in Rio Grande do Sul State, Brazil: classical and multilevel analysis A.B. Moraes, R.R. Zanini, J. Riboldi, E.R.J. Giugliani Cad. Saúde Pública, Rio de Janeiro, 28(12):2293-2305, dez, 2012; http://www.scielo.br/pdf/csp/v28n12/08.pdf
Risk factors for low birth weight in the public-hospitals at Peshawar, NWFP-Pakistan S. Badshah, L. Mason, K.Mc. Kelvie, R. Payne, P.J.G. Lisboa BMC Public Health 2008, 8:197; doi:10.1186/1471-2458-8-197
Risk factors associated with low birth weight of neonates among pregnant women attending a referral hospital in northern Tanzania J.E. Siza Tanzan J Health Res. 2008 Jan;10(1):1-8; http://www.ncbi.nlm.nih.gov/pubmed/18680958
Urinary lactate/creatinine ratio as early predictor of hypoxic ischaemic encephalopathy in term neonates admitted to NICU, Zagazing University hospitals M. A. Badr, Y.F. Ali, M. A. Abdelhady [et al.] Res. J. Medicine & Med. Sci. 2011;6(2):54-61; http://www.aensiweb.com/old/rjmms/rjmms/2011/54-61.pdf
Copyright (c) 2016 INTERNATIONAL NEUROLOGICAL JOURNAL
This work is licensed under a Creative Commons Attribution 4.0 International License.
Our edition uses the copyright terms of Creative Commons for open access journals.
Authors, who are published in this journal, agree with the following terms:
- The authors retain rights for authorship of their article and grant to the edition the right of first publication of the article on a Creative Commons Attribution 4.0 International License, which allows others to freely distribute the published article, with the obligatory reference to the authors of original works and original publication in this journal.
- Directing the article for the publication to the editorial board (publisher), the author agrees with transmitting of rights for the protection and using the article, including parts of the article, which are protected by the copyrights, such as the author’s photo, pictures, charts, tables, etc., including the reproduction in the media and the Internet; for distributing; for the translation of the manuscript in all languages; for export and import of the publications copies of the writers’ article to spread, bringing to the general information.
- The rights mentioned above authors transfer to the edition (publisher) for the unlimited period of validity and on the territory of all countries of the world.
- The authors guarantee that they have exclusive rights for using of the article, which they have sent to the edition (publisher). The edition (the publisher) is not responsible for the violation of given guarantees by the authors to the third parties.
- The authors have the right to conclude separate supplement agreements that relate to non-exclusive distribution of their article in the form in which it had been published in the journal (for example, to upload the work to the online storage of the journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this journal is included.
- The policy of the journal permits and encourages the publication of the article in the Internet (in institutional repository or on a personal website) by the authors, because it contributes to productive scientific discussion and a positive effect on efficiency and dynamics of the citation of the article.
- The rights to the article are deemed transferred by the authors to the edition (the publisher) since the moment of the publication of the article in the printed or electronic version of journal.