DOI: https://doi.org/10.22141/2224-0713.4.74.2015.78210

Perinatal Risk Factors for Hypoxic-Ischemic Encephalopathy in Full-Term Infants with Normal and Low to the Gestational Age Body Weight

Ye.P. Ortemenka

Abstract


In the department of neonatal pathology of the Chernivtsi regional children’s clinical hospital, 41 full-term newborns with hypoxic-ischemic encephalopathy have been examined with the aim of studying perinatal risk factors of the disease depending on birth weight. It is found that the main predictors of hypoxic-ischemic encephalopathy in small for gestational age infants were: mothers’ residence in urban areas (46.2 %); presence of chronic maternal disease (anemia, thyroid pathology) during pregnancy (46.6 %); concomitant congenital malformations in one third (30.8 %) of newborns; development of respiratory disorders at birth, requiring artificial lung ventilation (61.5 %); infants’ feeding problems (61.5 %). Hypoxic-ischemic lesions of the central nervous system in full-term neonates with adequate to the gestational age body weight were preceded by: pathological course of intrapartum period (fetal distress during labor due to tight nuchal cord in one fourth of cases and pathological delivery in one third (32.1 %) of cases), associated with the birth of one-third of neonates with asphyxia (Apgar 1st minute test ≤ 4 points), which often led to the development of cardiogenic complications (28.6 %), multiple organ failure (14.3 %) and seizure syndrome (17.9 %).


Keywords


hypoxic-ischemic encephalopathy; low to the gestational age body weight; perinatal risk factors

References


Pal'chyk A.B. Hypoksychesky-yshemycheskaya entsefalopatyya novorozhdennih / A.B. Pal'chyk, N.P. Shabalov. – 4-e yzd., yspr. y dop. – M.: MED-press-ynform, 2013. – 288 s.

Posledstvyya perynatal'nikh porazhenyy tsentral'noy nervnoy systemi: dyskussyonnie voprosi / A.P. Volosovets, S.P. Kryvopustov, Y.A. Lohynova, M.A. Shakot'ko // Zdorov'e rebenka. – 2008. - #4 (13). – S. 101-106.

Antepartum and Intrapartum Factors Preceding Neonatal Hypoxic-Ischemic Encephalopathy M. Martinez-Biarge, J. Diez-Sebastian, C.J. Wusthoff, E. Mercuri, F.M. Cowan Pediatrics 2013;132;e952; originally published online September 9, 2013; DOI: 10.1542/peds.2013-0511

Risk factors for hypoxic-ischaemic encephalopathy in asphyxiated newborn infants / S. Futrakul, P. Praisuwanna, P. Thaitumyanon J Med Assoc Thai 2006; 89 (3): 322-8; http://www.medassocthai.org/journal

Incidence and prediction of outcome in hypoxic-ischaemic encephalopathy in Japan M. Hayakawa, Y. Ito, S. Saito, N. Mitsuda [et al] Pediatrics International 2014;56:215–221; doi: 10.1111/ped.12233

Obstetric aspects of hypoxic ischemic encephalopathy S. Kumar, S. Paterson-Brown Early Hum Dev. 2010 Jun;86(6):339-44. doi: 10.1016/j.earlhumdev.2010.05.009.

Perinatal morbidity and risk of hypoxic-ischaemic encephalopathy assotiated with intrapartum sentinel events M. Martinez-Biarge, R. Madero, A. Gonzalez, J. Quero [et al] Am J Obstet Gynecol 2012;206:148-154; doi: 10.1016/j.ajog.2011.09.031

Prediction of perinatal hypoxic encephalopathy: proximal risk factors and short-term complications T.Y.Y. Zamzami, S.A. Al-Saedi, A.M. Marzouki, H.A. Nasrat J Clin Gynecol Obstet. 2014;3(3):97-104; doi: http://dx.doi.org/10.14740/jcgo267w

Risk factors for low birth weight in Rio Grande do Sul State, Brazil: classical and multilevel analysis A.B. Moraes, R.R. Zanini, J. Riboldi, E.R.J. Giugliani Cad. Saúde Pública, Rio de Janeiro, 28(12):2293-2305, dez, 2012; http://www.scielo.br/pdf/csp/v28n12/08.pdf

Risk factors for low birth weight in the public-hospitals at Peshawar, NWFP-Pakistan S. Badshah, L. Mason, K.Mc. Kelvie, R. Payne, P.J.G. Lisboa BMC Public Health 2008, 8:197; doi:10.1186/1471-2458-8-197

Risk factors associated with low birth weight of neonates among pregnant women attending a referral hospital in northern Tanzania J.E. Siza Tanzan J Health Res. 2008 Jan;10(1):1-8; http://www.ncbi.nlm.nih.gov/pubmed/18680958

Urinary lactate/creatinine ratio as early predictor of hypoxic ischaemic encephalopathy in term neonates admitted to NICU, Zagazing University hospitals M. A. Badr, Y.F. Ali, M. A. Abdelhady [et al.] Res. J. Medicine & Med. Sci. 2011;6(2):54-61; http://www.aensiweb.com/old/rjmms/rjmms/2011/54-61.pdf




Copyright (c) 2016 INTERNATIONAL NEUROLOGICAL JOURNAL

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

 

© Publishing House Zaslavsky, 1997-2018

 

   Seo анализ сайта