The Impact of Solar Exposure and Vitamin D Status on Сlinical Сharacteristics of Patients with Multiple Sclerosis in the Population of Vinnytsia Region

S.L. Malyk, S.P. Moskovko, A.V. Kostiuchenko

Abstract


The objective of this study was to evaluate the correlation between sun exposure, serum 25-hydroxycholecalciferol (25(OH)D) and depressive symptoms, feeling of anxiety, fatigue, cognitive impairment in patients with multiple sclerosis (MS) in the population of Vinnytsia region. We have analyzed data received from 77 MS patients. The prevalence of vitamin D deficiency — 35.1 %. Index of body supply of vitamin D inversely correlated with depressive symptoms (r = –0.251; p = 0.026), fatigue (r = –0.342; p = 0.002), age (r = –0.248; p = 0.030). High levels of solar exposure inversely correlated with EDSS score (r = –0.256; p = 0.024) and a lower severity of depressive symptoms (r = –0.227; p = 0.047) in patients with MS in the population of Vinnytsia region.


Keywords


multiple sclerosis; sun exposure; vitamin D; depression; fatigue; Vinnytsia region

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DOI: https://doi.org/10.22141/2224-0713.5.75.2015.78029

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