Email this article DOI: https://doi.org/10.22141/2224-0713.5.75.2015.78024
Prevalence of Cardiovascular Risk Factors in the Elderly with «Silent» Brain Infarctions
Abstract
The comparative study of the structure and significance of cardiovascular risk factors for «silent» brain infarctions in 404 patients (202 persons with magnetic resonance signs of «silent» brain infarctions, 202 — without them), aged from 62 to 78 years, has shown that arterial hypertension (p < 0.01), abdominal obesity (p < 0.01), smoking (p < 0.05), high blood serum level of creatinin (p < 0.05), and obstructive sleep apnoe (p < 0.05) were risk factors for «silent» brain infarctions in the elderly population of Ukraine. In terms of «silent» brain infarct formation, the most adverse was a simultaneous presence of 3 (p < 0.01) or 4 (p < 0.03) cardiovascular risk factors. The gender factor was significantly associated with arterial hypertension (p < 0.01), abdominal obesity (p < 0.05), and smoking (p < 0.03), but it was not an independent risk factor for «silent» brain infarctions. The study demonstrated a range of significance of specific cardiovascular risk factors for «silent» brain infarctions in the elderly and revealed the importance of further research of the role of a combined impact of risk factors for «silent» brain infarctions.
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Fanning J.P. The epidemiology of silent brain infarction: a systematic review of population-based cohorts / J.P. Fanning, A.A. Wong, J.F. Fraser // BMC Med. — 2014. — V. 12. — P. 119-129.
Lim J.S. Risk of «silent stroke» in patients older than 60 years: risk assessment and clinical perspectives / J.S. Lim, H.M. Kwon // Clin. Interv. Aging. — 2010. — V. 5. — P. 239-251.
Prevalence and risk factors of cerebral white matter changes and silent infarcts on brain computed tomography scans among community-dwelling healthy adults: The PRESENT project Hyunyoung / Н. Park, J.H. Jo, J.S. Cheong et al. // Neurology Asia. — 2014. — V. 19, № 4. — P. 351-356.
The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications / C. Iber, S. Ancoli-Israel, A. Chesson, S.F. Quan et al. — 1st ed. — Westchester: American Academy of Sleep Medicine, IL, 2007.
2013 ESH/ESC Guidelines for the management of arterial hypertension / G. Mancia, R. Fagard, K. Narkiewicz et al. // J. Hypertension. — 2013. — V. 31, № 7. — P. 1281-1357.
Grundy S.M. An International Atherosclerosis Society position paper: Global recommendations for the management of dyslipi-demia / M.S. Grundy et al. // J. Clin. Lipidology. — 2013. — V. 7, Issue 6. — P. 561-565.
The 'silence' of silent brain infarctions may be related to chronic ischemic pre-conditioning and nonstrategic locations rather than to a small infarction size / C. Feng, X. Bai, Y. Xu et al. // Clinics. (Sao Paulo). — 2013. — V. 68, № 3. — P. 365-369.
Obstructive sleep apnea as a risk factor for silent cerebral infarction / E.R. Cho, H. Kim, H.S. Seo et al. // J. Sleep Res. — 2013. — V. 22, № 4. — P. 452-458.
Obstructive sleep apnea as a risk factor for cerebral white matter change in a middle-aged and older general population / H. Kim, C.H. Yun, R.J. Thomas et al. // Sleep. — 2013. — V. 36, № 5. — P. 709-715B.
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