Adjuvant Therapy in Chronic Pain Syndrome (Scientific Review)

І.А. Yevtushenko, V.V. Marusychenko


The problem of chronic pain is an important and significant in many countries due to the high prevalence and diversity of forms. Opioid and non-opioid analgesics are applied for the treatment. Currently, adjuvants have been widely used. The main action of these pharmacological agents is not analgesia, but they can complement the action of analgesics, making it more efficient. The pharmacokinetic characteristics of pregabalin make it possible to use it in chronic pain syndrome, especially of neurogenic origin, for the treatment of which polypharmacotherapy is often used — both to reduce the pain, and to treat the comorbidity.


chronic pain syndrome; anesthesia; adjuvants; pregabalin


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