Damage to the nervous system associated with HIV infection (a clinical case)

Authors

  • A.L. Sidelkovsky Clinic of Modern Neurology “AKSIMED”, Kyiv, Ukraine; Bogomolets National Medical University, Kyiv, Ukraine
  • P.A. Fedorov Clinic of Modern Neurology “AKSIMED”, Kyiv, Ukraine; Bogomolets National Medical University, Kyiv, Ukraine
  • V.V. Marusichenko Clinic of Modern Neurology “AKSIMED”, Kyiv, Ukraine; Bogomolets National Medical University, Kyiv, Ukraine
  • M.R. Ignatischev Clinic of Modern Neurology “AKSIMED”, Kyiv, Ukraine; Bogomolets National Medical University, Kyiv, Ukraine

DOI:

https://doi.org/10.22141/2224-0713.16.8.2020.221963

Keywords:

neuro-AIDS, AIDS dementia, HIV-associated myelopathy, HIV-associated encephalopathy

Abstract

In Eastern Europe, at least 130 thousand new cases of HIV infection have been registered, which undoubtedly reflects the urgency of this medical problem. In our country, the average rate of human immunodeficiency infection is 58 cases per 100 thousand people. It is known that the disease is caused by an RNA-containing human immunodeficiency virus. Two types of it have been studied — HIV-1 and HIV-2, which have many subtypes. An important clinical feature of this virus is its tropism to cells of the human nervous and immune systems. The main risk group for the disease is injecting drug users, blood recipients, and people with low social responsibility. The impairment of the nervous system in AIDS is represented by the AIDS-dementia complex, acute aseptic meningitis, HIV-associated myelopathy, pathology of the peripheral nervous system, as well as the influence of opportunistic infections and neoplasms. This article presents a clinical case of lesions of the nervous system associated with HIV infection and also considers the etiology, pathogenesis, features of the course, diagnosis, and treatment of patients with neuro-AIDS.

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Published

2020-11-01

Issue

Vol. 16 No. 8 (2020)

Section

To practicing Neurologist

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