Strategy of membrane protection in pharmacotherapy of vascular cognitive impairment

Authors

  • S.G. Burchinsky State Institution “D.F. Chebotarev Institute of Gerontology of the National Academy of Medical Sciences of Ukraine”, Kyiv, Ukraine

DOI:

https://doi.org/10.22141/2224-0713.16.8.2020.221959

Keywords:

cognitive dysfunction, mild cognitive impairment syndrome, cerebrovascular pathology, citicoline

Abstract

The article considers modern views on the problem of vascular cognitive dysfunction, in particular, on the nature and options of treatment of mild cognitive impairment syndrome as one of the most common forms of cognitive decline in the elderly and senile patients. From this point of view, the requirements for the selection of the optimal pharmacological tool for pharmacotherapy and pharmacoprophylaxis of this syndrome, especially the strategy of membrane protection, are analyzed. Particular attention is paid to the mechanisms of action and features of clinical use of Lira (citicoline) — a drug with unique clinical and pharmacological properties that allow implementing a strategy of pathogenetically sound neuro- and geroprotective pharmacotherapy in cerebrovascular disorders. Mechanisms of action, clinical efficacy of Lira (citicoline), safety characteristics and recommendations for practical use of the drug are considered in detail.

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Published

2021-03-10

Issue

Vol. 16 No. 8 (2020)

Section

To practicing Neurologist

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