Non-psychotic mental disorders in young men with epilepsy


  • A. Voitiuk Kharkiv Medical Academy of Postgraduate Education, Kharkiv, Ukraine
  • T. Litovchenko Kharkiv Medical Academy of Postgraduate Education, Kharkiv, Ukraine



epilepsy, comorbid disorders, non-psychotic mental disorders, neuropsychological testing, epilepsy in young men


Background. Epilepsy is one of the most important clinical problems and at the same time it is an interdisciplinary challenge. Comorbid disorders in epilepsy represent an extensive heterogeneous group of various conditions, most of which are mental disorders (personality disorder, dementia, depression, anxiety disorders, psychoses). The objective is to study the comorbidity of epilepsy and non-psychotic mental disorders in young men and the characteristics of its impact on the quality of life of a patient. Materials and methods. This study analyzed data from neuropsychological testing of 40 men aged 18–44 years. The correlation analysis (Pearson correlation coefficient) was used to determine the degree and nature of the relationship between the study parameters. All the differences and relationships mentioned in the article were considered statistically valid at p < 0.05. Results. All patients in this study were found to have non-psychotic mental disorders in the form of anxiety, concern about their health, and a decrease in self-esteem. Personal and situational anxiety averaged 45.60 ± 0.35 points. One of the most common non-psychotic disorders in individuals with epilepsy is organic personality disorder. Analysis on the International Personality Disorder Examination scale showed that 32 people (80 %) had organic personality disorder due to epilepsy. The depression is the most common comorbidity observed in individuals with epilepsy. An analysis of the data of 40 people using Hamilton Depression Rating Scale showed that mild depressive disorders were observed in 18 (45 %) people, moderate — in 12 (30 %), and severe depressive disorders — in 10 patients (25 %). The depth of manifestations of depression correlated with the duration of the disease (r = 0.39; p < 0.05), introversion (r = 0.33; p < 0.05), age (r = 0.29; p < 0.05) and polytherapy (r = 0.53; p < 0.05). Conclusions. Thus, we have identified non-psychotic mental disorders such as organic personality disorder, dementia, depression, which are typical for epilepsy in young men.


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