Epidemiology of Parkinson’s disease in the Southern Ukraine
Background. Parkinson’s disease (PD) is a slowly progressing neurodegenerative disease with accumulation of alpha-synuclein and the formation of Lewy bodies inside nerve cells. The prevalence of PD ranges from 100 to 200 cases per 100,000 population. However, in the Ukrainian reality, many cases of the disease remain undiagnosed, which affects the statistical indicators of incidence and prevalence. The purpose of the study is to compare PD epidemiological indices in the Southern Ukraine with all-Ukrainian rates. Material and methods. Statistical data of the Ministry of Health of Ukraine, public health departments of Odesa, Mykolaiv and Kherson regions for 2015–2017 were analyzed. There were used the methods of descriptive statistics and analysis of variance. Results. Average prevalence of PD in Ukraine is 67.5 per 100,000 population — it is close to the Eastern European rate. The highest prevalence was registered in Lviv (142.5 per 100,000), Vinnytsia (135.9 per 100,000), Cherkasy (108.6 per 100,000) and Kyiv (107.1 per 100,000) regions. The lowest rates were in Luhansk (37.9 per 100,000), Kyrovohrad (42.5 per 100,000), Chernivtsi (49.0 per 100,000) and Ternopil (49.6 per 100,000) regions. In the Southern Ukraine, the highest prevalence of PD was found in Mykolaiv region. The prevalence was higher in urban area and in the districts located closely to the regional capital city. Based on the total population and demographic characteristics of Odesa, Mykolaiv and Kherson regions, it can be concluded that at least 40–50 % of patients with PD are left outside the sphere of medical care, and in some areas, this index is 80–90 %. Conclusions. To optimize the diagnostic process and standardize epidemiological data, it is necessary to intensify the work of centers of extrapyramidal diseases in all regions of Ukraine, including intracenter and intercenter information databases to obtain adequate and pertinent statistical data.
Гринхальх Т. Основы доказательной медицины: пер. с англ.; под ред. И.Н. Денисова [и др.]. 4-е изд., перераб. и доп. Москва:
ГЭОТАР-Медиа, 2015. 330 с.
Kalia L.V., Lang A.E. Parkinson’s disease. Lancet. 2015 Aug 29. 386(9996). 896-912.
Tysnes O.B., Storstein A. Epidemiology of Parkinson’s disease.
J. Neural Transm. (Vienna). 2017 Aug. 124(8). 901-905.
Dorsey E.R., Bloem B.R. The Parkinson pandemic — a call to action. JAMA Neurol. 2018 Jan 1. 75(1). 9-10.
Tanguy A., Jönsson L., Ishihara L. Inventory of real world data sources in Parkinson’s disease. BMC Neurol. 2017 Dec 8. 17(1). 213.
Левин О.С., Федорова Н.В. Болезнь Паркинсона: научное издание. 3-е изд. Москва: МЕДпресс-информ, 2012.
Bridgeman K., Arsham T. The Comprehensive guide to Parkinson’s disease. NY: Viartis, 2017. 804 p.
Romaniuk P., Semigina T. Ukrainian health care system and its chances for successful transition from Soviet legacies. Global Health. 2018. 14(1). 116.
Trufanov Y.O., Svyrydova N.K., Galusha A.I., Chupryna G.M., Popov O.V., Nechkalyuk M.V. Prevalence of Parkinson’s disease in Ukraine. MDS 2016 International Congress. Abstract 443. URL: https://www.mdsabstracts.org/abstract/prevalence-of-parkinsons-disease-in-ukraine.
Труфанов Е.А., Головченко Ю.И., Слободин Т.Н., Суховерская О.Н. Эпидемиология болезни Паркинсона в Украине. Международный неврологический журнал. 2012. 7(55). 42-46.
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