DOI: https://doi.org/10.22141/2224-0713.16.2.2020.200958

The diagnosis of difficult to treat limb-girdle muscular dystrophy using the magnetic resonance imaging method (scientific review and own observation)

H.V. Palahuta, V.I. Smolanka, I.Yu. Dutka

Abstract


Limb-girdle muscular dystrophy is a diverse group of genetically heterogeneous muscle disorders, usually characterized by slowly progressing muscle weakness. New forms of these disorders are being identified constantly, their nosology and nomenclature are often confusing. Limb-girdle muscular dystrophies are rare disorders and often present a diagnostic problem. The combination of clinical, radiological and laboratory examinations is of great importance for the referral to genetic diagnosis. A comprehensive neurological history and examination should precede any genetic testing. Muscle magnetic resonance imaging is increasingly used to give clues in the diagnosis of muscular dystrophy (including limb-girdle muscular dystrophy), based on specific patterns of signal changes in different muscles in different parts of the limbs.

Keywords


muscle magnetic resonance imaging; limb-girdle muscular dystrophy; genetics; specific patterns of muscle damage

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