Pain and depression: new possibilities of pharmacotherapy of chronic psychogenic pain syndromes

S.G. Burchinsky


Тhe present paper considers modern views on the problem of chronic psychogenic pain and its association with depressive disorders. From this point of view, the requirements to the choice of optimal pharmacological tool within comprehensive therapy of psychogenic pain and depression have been analyzed. A main attention is paid to the mechanisms of action and peculiarities of the clinical use of duloxetine (Dyulok) — antidepressant with unique mechanism of action and clinico-pharmacological properties that make possible to realize the strategy of pathogenetic pharmacotherapy in the treatment of depression and chronic psychogenic pain syndromes. A clinical efficacy of duloxetine (Dyulok), its safety characteristics, and recommendations of practical use have been considered in detail.


chronic psychogenic pain syndromes; depression; antidepressants; duloxetine


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