Comparison of chronic pain signs caused by interstitial cystitis versus lumbalgia
Background. Interstitial cystitis is still a poorly-diagnosed disease and one of the most common causes of chronic pelvic pain. Since pain in the back is one of the most common complaints during a visit to a doctor, comparing the features of chronic pain in heterogeneous (dissimilar) groups of patients may constitute clinical and scientific interest due to better understanding of the universal pathophysiological mechanisms of chronic pain syndrome in patients of different profile. Materials and methods. The study was conducted in outpatient setting with a total of 59 patients: 44 were diagnosed with interstitial cystitis, 15 had lumbalgia. For assessment of symptoms and impact on quality of life, patients of the first group were questioned using: Genitourinary Pain Index, O’Leary-Sant Questionnaire and Pelvic Pain and Urgency/Frequency Patient Symptom Scale. Pain evaluation in both groups was performed by Visual Analog Scale and McGill Questionnaire. Results. The intensity of pain in the first group (Visual Analog Scale) was 5.30 ± 1.13, whereas in patients with lumbalgia — 4.73 ± 0.88 (p = 0.058), no sex-dependent difference was found in both groups. The mean age of symptoms onset in patients of the first group predominated by more than 10 years (49.20 ± 10.41 years versus 38.33 ± 14.14 years, respectively, p = 0.013). The number of selected McGill questionnaire pain descriptors showed significant variability, but the average values did not differ significantly between groups (12.18 ± 5.81 versus 10.73 ± 5.11, p = 0.368). Most frequently selected descriptors in the first group were: aching (93.2 %) and pulling (77.3 %); in patients with lumbalgia — pulling (100.0 %) and twisting (66.7 %). A strong correlation relationship (r = 0.71) was found between the groups by the frequency of the most common pain characteristics selection. Conclusions. The revealed common features of chronic pain syndrome between groups included the choice of similar McGill grade pain descriptors. However, the intensity of pain in the first group was slightly prevailing, despite the increased duration of disease in patients with lumbalgia. This consequently requires additional study of the comparable groups with homogenized duration of symptoms.
Full Text:PDF (Українська)
Merskey H, Bogduk N. Classification of Chronic Pain. Seattle: IASP Press; 1994. 222p.
Berry SH, Bogart LM, Pham C, et al. Development, validation, and testing of an epidemiological case definition of interstitial cystitis/painful bladder syndrome. J Urol. 2010;183:1848-52. doi: 10.1016/j.juro.2009.12.103
Parsons CL, Tatsis V. Prevalence of interstitial cystitis in young women. Urology. 2004;64:866-70. doi: 10.1016/j.urology.2004.06.044
Temml C, Wehrberger C, Riedl C, Ponholzer A, Marszalek M, Madersbacher S. Prevalence and correlates for interstitial cystitis symptoms in women participating in a health screening project. Eur Urol. 2007;51:803-8. doi: 10.1016/j.eururo.2006.08.028
Onopko VF, Kirilenko EA, Baranova EO, Golubeva VS. Interstitial cystitis or bladder pain syndrome: current view on a problem. Bulletin of East-Siberian Scientific Center of Siberian Department of Russian Academy of Medical Sciences. 2016;1(107):65-9. (In Russian).
Barry MJ, Link CL, McNaughton-Collins MF, McKinlay JB. Overlap of different urological symptom complexes in a racially and ethnically diverse, community-based population of men and women. BJU Int. 2008;101:45-51. doi: 10.1111/j.1464 410X.2007.07191.x
Peeker R, Fall M. Toward a precise definition of interstitial cystitis: further evidence of differences in classic and non-ulcer disease. J Urol. 2002;167:2470-2. pmid: 11992059
Mattox TF. Interstitial cystitis in adolescents and children: a review. J Pediatr Adolesc Gynecol. 2004;17:7-11. doi: 10.1016/j.jpag.2003.11.003
Deyo RA, Weinstein JN. Low back pain. N Engl J Med. 2001;344:363-70. doi: 10.1056/NEJM200102013440508
Andersson GBJ. The epidemiology of spinal disorders. In: Frymoyer JW, ed. The adult spine: principles and practice. 2nd ed. New York: Raven Press, 1997:93-141.
Suri P, Boyko EJ, Goldberg J, Forsberg CW, Jarvik JG. Longitudinal associations between incident lumbar spine MRI findings and chronic low back pain or radicular symptoms: retrospective analysis of data from the longitudinal assessment of imaging and disability of the back (LAIDBACK). BMC Musculoskelet Disord. 2014;15:152. doi: 10.1186/1471-2474-15-152
Atlas S.J., Deyo R.A., Patrick D.L. et al. The Quebec Task Force classification for Spinal Disorders and the severity, treatment, and outcomes of sciatica and lumbar spinal stenosis. Spine. 1996;21(24):2885–92. pmid: 9112713 Jensen MC, Brant-Zawadzki MN, Obuchowski N, Modic MT, Malkasian D, Ross JS. Magnetic resonance imaging of the lumbar spine in people without back pain. N Engl J Med. 1994;331(2):69–73. doi: 10.1056/NEJM199407143310201
Clemens JQ, Calhoun EA, Litwin MS, et al. Validation of a modified National Institutes of Health chronic prostatitis symptom index to assess genitourinary pain in both men and women. Urology. 2009;74(5):983-7. doi: 10.1016/j.urology.2009.06.078
Lubeck DP, Whitmore K, Sant GR, Alvarez-Horine S, Lai C. Psychometric validation of the O’leary-Sant interstitial cystitis symptom index in a clinical trial of pentosan polysulfate sodium. Urology. 2001;57:62-6. pmid: 11378052
Parsons CL, Dell J, Stanford EJ et al. Increased prevalence of interstitial cystitis: previously unrecognized urologic and gynecologic cases identified using a new symptom questionnaire and intravesical potassium sensitivity. Urology. 2002;60:573-8. pmid: 12385909
Gerlinger C, Schumacher U, Faustmann T, Colligs A, Schmitz H, Seitz C. Defining a minimal clinically important difference for endometriosis-associated pelvic pain measured on a visual analog scale: analyses of two placebo-controlled, randomized trials. Health Qual Life Outcomes. 2010;8:138. doi: 10.1186/1477-7525-8-138
Melzack R. The McGill Pain Questionnaire: major properties and scoring methods. Pain. 1975;1(3):277-99. pmid: 1235985
Copyright (c) 2019 INTERNATIONAL NEUROLOGICAL JOURNAL
This work is licensed under a Creative Commons Attribution 4.0 International License.
© Publishing House Zaslavsky, 1997-2020