Bone mineral density, fat and lean mass in stroke patient
Background. Stroke and osteoporosis is an agedependent pathology that affects elderly people mostly. The purpose of the study was to evaluated bone mineral density (BMD), fat mass, lean mass and their relationship in stroke patients. Materials and methods. We examined 84 stroke patients and 124 persons of the corresponding age and sex without neurological pathology, who made up the comparison group. BMD, fat mass and lean mass were determined using dualenergy Xray absorptiometry. Results. The frequency of osteoporosis was significantly higher in stroke men and women than in the comparison group (12.5 versus 1.7 % and 20.5 versus 6.0 %, respectively). BMD in stroke women was significantly lower at all level observed, in men differences were recorded at distal radius and in the total body. The lean mass was significantly lower in stroke men (54.29 ± 1.22 and 58.02 ± 0.85 kg; p < 0.05), and the fat mass was significantly lower (32.42 ± 1.92 and 36.71 ± 1.15 kg; p < 0.05) in stroke women in comparison with control group. The men of both groups showed positive correlation between the BMD of the total body and the lean mass. Stroke women have positive relationships between fat mass and the BMD of the femoral neck, upper limbs, total body and significant correlation between fat mass and all regions of the skeleton. Conclusions. The results of our study show that stroke is a risk factor for the development of osteoporosis and emphasize the role of fat and lean mass in the development of osteoporosis in stroke patients.
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