DOI: https://doi.org/10.22141/2224-0713.3.97.2018.133683

The use of topiramate in paroxysmal and non-paroxysmal states in children (scientific review and personal observation)

S.К. Yevtushenko, O.Yu. Sukhonosova, A.A. Omelianenko

Abstract


he article deals with foreign publications for the last 10 years on the application of topiramate in children. The focus is on the use of topiramate as an antiepileptic drug. Particular emphasis is placed on the experience of topiramate off-label use — in young children, infants, at status epilepticus. Experience of using topiramate in non-paroxysmal (non-epileptic) states has also been accumulated. Proven importance of this drug in the prevention of migraine in children was demonstared. Fairly good tolerability profile is reflected, and attention was concentrated on drug-specific adverse events and measures to prevent them.

Keywords


epilepsy; children; topiramate

References


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