DOI: https://doi.org/10.22141/2224-0713.2.96.2018.130485

The choice of pregabalin — a modern approach to pain therapy in lumbosacral radiculopathy

T. Chistyk

Abstract


The review deals with the relevance of the problem of lumbosacral radiculopathy. Epidemiological data, causes, mechanisms of development, clinical picture and methods of pharmacotherapy in this pathology are presented. The guidelines of the international organizations for pain management, which recommend the use of pregabalin as first-line therapy, are considered. The efficacy and safety of pregabalin in the treatment of neuropathic pain has been studied in a number of clinical randomized trials that have demonstrated not only the analgesic effect of the drug but also the regression of concomitant affective disorders and insomnia in patients with lumbosacral radiculopathies.

Keywords


lumbosacral radiculopathy; pain syndrome; pregabalin

References


Argoff C., Wheeler A., Backonja M. Spinal and radicular pain syndromes. — Philadelphia, WB Saunders: Neurologic Clinics, 1998. — 833-45.

Подчуфарова Е.В. Боль в пояснично-крестцовой области: диагностика и лечение // РМЖ. — 2004. — № 10. — C. 581-584.

Воробьева О. Консервативное лечение пояснично-крестцовой радикулярной боли // Врач. — 2014. — № 9. — С. 8-11.

Skouen J.S., Brisby H., Otani K. et al. Protein markers in cerebrospinal fluid in experimental nerve root injury // Spine. — 1999. — 24. — 2195-200.

Goldberg M.S., Scott S.C., Mayo N.E. A review of the association between cigarette smoking and the development of non specific back pain and related outcomes // Spine. — 2000. — 25. — 995-1014.

Tarulli A.W. Lumbosacral radiculopathy // Neurol. Clin. — 2007. — 25 (2). — 387-405.

Хабиров Ф.А. Клиническая неврология позвоночника. —

Казань, 2003. — С. 147.

Левин О.С. Современные подходы к диагностике и лечению боли в спине. — М., 2006.

Данилов А.Б. Фармакотерапия нейропатической боли в спине // Consilium medicum. — 2011. — № 1.

Gatchel R.J., Gardea M.A. Lower back pain: psychosocial issues. Their importance in predicting disability, response to treatment and search for compensation // Neurologic clinics. — 1999. — 17. — 149-66.

Birklein F. Mechanism-based treatment principles of neuropathic pain // Fortschr. Neurol. Psychiatr. — 2002. — 70 (2). — 88-94.

Косарев В.В., Бабанов С.А. Профессиональные болезни. — М.: ГЭОТАР-Медиа, 2010. — 368 с.

Мухин Н.А., Косарев В.В., Бабанов С.А., Фомин В.В. Профессиональные болезни. — М.: ГЭОТАР-Медиа, 2013. —

с.

Rathwell J. Rational use of interventional modalities for the treatment of pain of spinal origin // Pain. — 2008-Updated review. — Seattle: IASP press, 2008. — P. 329-338.

Вейн A.M., Власов Н.А. Патогенез вегетативных нарушений при остеохондрозе позвоночника // Проблемы патологии позвоночника. — М., 1972. — С. 56-62.

Попелянский Я.Ю. Ортопедическая неврология (вертеброневрология): руководство для врачей. — М.: МЕДпресс-информ, 2011.

Johnson E.W., Fletcher F.R. Lumbosacral radiculopathy: review of 100 consecutive cases // Arch. Phys. Med. Rehabil. — 1981. — Vol. 62, № 7. — P. 321-323.

Tolle T., Dukes E., Sadosky A. Patient burden of trigeminal neuralgia: results from a cross-sectional survey of health state impairment and treatment patterns in six European countries // Pain Pract. — 2006. — Vol. 6 (3). — P. 153-160.

http: //www.dissercat.com/content/kliniko-fiziologicheskii-analiz-bolevogo-sindroma-pri-poyasnichno-kresttsovoi-radikulo­patii#ixzz58nRjlZzt.

Finnerup N.B., Otto M., McQuay H.J. et al. Algorithm for neuropathic pain treatment — an evidence based proposal // Pain. — 2005. — Vol. 118 (3). — P. 289-305.

Clinical practice guidelines for management of neuropathic pain: expert panel recommendations for South Africa / Chetty S., Baalbergen E., Bhigjee A.I. et al. // S. Afr. Med. J. — 2012. — № 102. — P. 312-325.

Hall G.C., Morant S.V., Carrol D. et al. An observational descriptive study of the epidemiology and treatment of neuropathic pain in a UK general population // BMC Family Practice. — 2013.

— 28.

Амелин А.В. Прегабалин в лечении спондилогенной радикулопатии // Русский медицинский журнал. — 2013. — № 10.

Baron R. et al. // Pain. — 2010. — 150. — 420-427.

Saldana M.T., Navarro A., Perez C. et al. Patient-reported-outcomes in subjects with painful lumbar or cervical radiculopathy treated with pregabalin: evidence from medical practice in primary care settings // Rheumatol. Int. — 2010. — Vol. 30 (8). — P. 1005-1015.

Taguchi T. et al. // Pain Res. — 2015, Aug 5. — 8. — 487-497.

Хабиров Ф.А., Есин Р.Г., Кочергина О.С., Хайбуллин Т.И., Ахметова Г.И., Васильева М.А., Еникеева Г.И., Исмагилова А.А., Каменев В.М., Хабирова Ю.Ф., Хузяшева Э.И. Прегабалин при лечении вертеброгенной корешковой боли // Consilium medicum [приложение]. Педиатрия. — 2008. — № 1.

Gore M., Dukes E., Rowbotham D.J. et al. Clinical characteristics and pain management among patients with painful peripheral neuropathic disorders in general practice settings // Eur. J. Pain. — 2007. — Vol. 11 (6). — P. 652-664.




Copyright (c) 2018 INTERNATIONAL NEUROLOGICAL JOURNAL

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

 

© Publishing House Zaslavsky, 1997-2020

 

   Seo анализ сайта