The modern view of the multiple sclerosis relapses treatment

G.G. Shkilnyuk, A.A. Bogdan, N.N. Burova, G.V. Kataeva, N.A. Samoilova, I.D. Stoliarov


In spite of decreasing incidence of multiple sclerosis relapses in disease-modifying treatment, the problem of relapses treatment is still actual. Every relapse contributes to stable neurological deficiency and, hence, the progress of invalidization. It should be noted, that it is not always possible to definitely evaluate the activity of disease because of the variable magnetic resonance picture: some focuses disappear or reduce, at the same time other focuses appear or increase. In this case, the use of magnetic resonance spectroscopy is advisable. Magnetic resonance spectroscopy helps to evaluate the activity of disease at the early stage and to assess the biochemical and neurophysiological signs of demyelination. We present the description of a difficult clinical case of the multiple sclerosis relapse and the evaluation of the metabolic response on the treatment by means of the magnetic resonance spectroscopy.
Hence, the treatment of multiple sclerosis relapses is very important because it helps to delay the invalidization. It is necessary to evaluate accurately all risks and advantages of every type of relapse treatment.


multiple sclerosis; relapses; magnetic resonance spectroscopy


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