Clinical and epidemiological characteristics of migraine and episodic syndromes that may be associated with migraine of children in the Khmelnytskyi region based on the retrospective research

L.V. Pypa, R.V. Svistilnik, S.P. Moskovko, V.I. Ruda, Yu.N. Lysytsia


The article presents the results of a retrospective research on the prevalence and clinical features of migraine and episodic syndromes that may be associated with migraine based on analysis of 9,469 case histories of children under 18 who were treated in the neurology, gastroenterology and endocrinology departments of Khmelnytskyi Regional Children’s Hospital in 2010–2014. During the research, we used the criterial approach to diagnose diseases of migraine’s range from the International Classification of Headache Disorders, 3rd edition (ICHD-III; beta version) 2013, in addition to detecting specific pathologies with episodic course and the absence of organic changes during the survey. As a result of the analysis, we identified 155 case records (65 boys and 90 girls) whose symptoms were coincided with the criteria of migraine diagnosis or episodic syndromes that may be associated with migraine. The findings demonstrated very low diagnostic level in these pathologies (0.21 % of all neurological diagnoses). After using the criterial approach, their number increased to 4.67 % in the structure of neurological pathologies. Typical symptoms of migraine are often interpreted within the diagnosis of vegetative-vascular dystonia. In the structure of the diagnosis of vegetative-vascular dystonia, migraine occupied 15.5 %. The diagnosis of syndromes associated with migraine was nearly absent. We have revealed that cyclic vomiting syndrome and abdominal migraine can often hide behind the diagnosis of acetonemic syndrome or functional dyspepsia. Using the criteria of ICHD-III (beta version), cyclic vomiting syndrome accounted for 2.8 % and abdominal migraine — 7.6 % in the structure of functional dyspepsia. In the structure of primary acetonemic syndrome, cyclic vomiting syndrome composed a high percentage (23.4 %).


migraine; episodic syndromes that may be associated with migraine; clinical pattern; epidemiology


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